Molecular analysis of familial polyposis coli
نویسندگان
چکیده
منابع مشابه
Familial adenomatous polyposis coli.
The other mode of treating these patients are subtotal colectomy with ileorectal anastomosis alongwith regular follow up with proctoscopy for development of cancer in retained rectal mucosa(3,7). Recently, Stevan et al. (8) utilized laproscope for total proctocolectomy as well as ileoanal anostomosis while others performed ileopouch anal anastomosis alongwith total proctocolectomy(9,10). Thus t...
متن کاملFamilial Polyposis Coli
observations which they regard as established facts. For example: in discussing patients with temporal lobe epilepsy (TLE), the statement is made, "interictal aggressiveness is a common feature but is relatively well tolerated by many of the families, probably because of the marked emotional warmth customarily displayed by these same patients toward the family members." To illustrate these poin...
متن کاملBest practice guidelines for molecular analysis of colorectal polyposis: familial adenomatous polyposis coli (FAP) and MUTYH-associated polyposis (MAP)
Background:. UK Clinical Molecular Genetics Society (CMGS) consensus best practice guidelines for molecular analysis of familial adenomatous polyposis coli (FAP) were published in 2000. Technological developments in molecular testing for FAP together with the clinical and molecular characterisation of MUTYH-associated polyposis (MAP) led to the need to update the original FAP guidelines which w...
متن کاملMolecular analysis of sulindac-resistant adenomas in familial adenomatous polyposis.
PURPOSE Sulindac causes the reduction of adenomas in familial adenomatous polyposis (FAP) patients, but complete regression is unusual, and breakthrough of colorectal carcinoma during sulindac treatment has been described. The molecular features related to sulindac resistance are unknown. Therefore, we investigated molecular alterations in adenomas from FAP patients with complete adenoma regres...
متن کاملThe Gene for Familial Polyposis Coli Maps
The inherited genetic defect in adenomatous polyposis has been localized to a small region on the long arm of chromosome 5. Sixteen DNA marker loci were used to construct a linkage map ofthe chromosome. When five kindreds segregating a gene for adenomatous polyposis coli were characterized with a number of the markers, significant linkage was found between one marker and the disease gene. Linka...
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ژورنال
عنوان ژورنال: Japanese journal of human genetics
سال: 1990
ISSN: 0021-5074
DOI: 10.1007/bf01883168